‘Call numbers for any exposure need context for readers to understand the relative size and scope of the potential problem. For perspective, in 2015 there were 263 Kratom-related calls to the NPDS compared to 55,151 diphenhydramine-related calls, 18,470 aspirin-related calls, and 1,355 involving nicotine. Depending on the substance category, many if not most calls do not require medical attention. For additional perspective, it is likely that there are at least 10 million and possibly as many as 16 million Kratom users in the US, indicating a very low risk of serious adverse events among Kratom users.’ By Kami Ann Davis
